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So now that we’ve covered NMN and how it can easily enter through the cell membrane and effectively raise NAD+ levels, let’s discuss in more detail some of the potential health benefits from taking NMN.
Mitochondria are the powerhouses of the cells. Without NAD+ the mitochondria could not power our cells, leading to cellular decay and disease.
Our muscles require a steady stream of nutrients to fuel its performance. NAD+ is critical in metabolizing key energy molecules such as glucose and fatty acids to supply our muscles with the fuel it needs.
The heart requires a tremendous amount of energy to continually pump and circulate blood throughout our entire body. NAD+ levels are essential in providing the energy required to keep our hearts pumping.
NMN is produced from B vitamins in the body. The enzyme responsible for making NMN in the body is called nicotinamide phosphoribosyltransferase (NAMPT). NAMPT attaches nicotinamide (a vitamin B3) to a sugar phosphate called PRPP (5’-phosphoribosyl-1-pyrophosphate). NMN can also be made from ‘nicotinamide riboside’ (NR) through the addition of a phosphate group.
‘NAMPT’ is the rate-limiting enzyme in the production of NAD+. This means lower levels of NAMPT cause decreased NMN production, resulting in decreased NAD+ levels. Adding precursor molecules like NMN can also speed up NAD+ production.
