What is Urolithin A
Urolithin A is a compound formed by gut bacteria by transforming polyphenols like ellagitannins. Consumption of foods rich in Ellagic Acid and ellagitannins increases the production of urolithin A in the body since both are its precursors. Urolithin A has been a subject of interest for scientists for over two decades in terms of its potential benefits for the human body.
Recent research has shown that urolithin A can help improve mitochondrial health. The way it helps mitochondrial health is by removing damaged mitochondria from the body through a process called mitophagy.
Urolithin A is unique in the fact that not everyone is capable of producing it naturally in their body. Urolithins A is produced in the stomach. However, some people’s microbiomes lack the bacteria that produce the substance.
Urolithin A supplements can ensure that those who cannot make urolithins A on their own can have the substance replenished in their system for all the necessary processes. Even the people who have microbiomes capable of producing urolithin A can benefit from urolithin A supplementation.
Urolithin A is important for many processes in the body. One of the most important processes that urolithin A participates in is recycling faulty mitochondria during aging. Urolithin A helps in the recycling process that takes uses faulty mitochondria to replace them with new healthier ones.
Benefits of Urolitin a
Since urolithin A is found in a range of tissues, it is theorized that it will impact many organs and systems in mice, cells, worms, and humans. Some of the benefits of urolithin A have been discussed in this section in detail.
- Mitophagy – One of the most important benefits of urolithin A is that it helps with a process called mitophagy.
Neuroprotection Against Cognitive Diseases – Another benefit of urolithin A is its ability to slow down the onset of cognitive diseases by reducing brain inflammation.
Anti-Inflammatory Benefits – A 2021 meta-study has shown that urolithin A can work as a potent anti-inflammatory agent in animal studies. Urolithin A has also shown an ability to provide anti-inflammatory benefits in preventing immunometabolic diseases.
Anti-Aging Benefits – As mentioned before, urolithin A helps improve mitophagy and mitochondrial health, two significant hallmarks of aging. Having looked at the extensive benefits of urolithin A in improving these hallmarks, it can be concluded that the supplement can be a candidate for anti-aging aid. The evidence for its anti-inflammatory also helps make its case for an anti-aging drug.