Magnolia (commonly known as Houpu) bark has been traditionally used as a herbal medicine in China and southeast Asia. Magnolol and Honokiol, two polyphenolic compounds that are commonly seen as the main active ingredients exist in magnolia bark have demonstrated have anti-bacterial, anti- inflammatory , anti –depression, weight loss and other properties. DHH-B, the abbreviation of dihydrohonokiol-B, is a variant of honokiol derived from magnolia bark. It is always used as a natural supplement for brain health, better sleep, stress reduction, and anxiety.


DHH-B works by increasing the effects of GABA, a neurotransmitter that inhibits excitatory neurons in the brain. It also supports better sleep and reduces anxiety levels. Another way DHH-B works is by activating the receptors for cannabinoids, natural receptors in your body. This activation serves to improve mood, relieve pain, and reduce inflammation. Due to its potent antioxidant properties, DHH-B also lowers inflammation levels and oxidative stress throughout your body. This compound can be taken by mouth.

DHH-B works to decrease the levels of adrenaline, which is a powerful biochemical released by the brain in times of chronic and severe stress. This biochemical increases alertness and vigilance. Reducing these levels is a significant benefit for those suffering from AFS. DHH-B also decreases very high levels of cortisol, which can lead to serious physical issues. When used as an anti-anxiety agent, DHH-B lowers anxiety without affecting respiration or motor skills. Researchers say its action is similar to benzodiazepines like diazepam, without the harmful side effects. Always check with your physician before starting these compounds.


Sleep Aids

Dihydrohonokiol-B works effectively as a sleep promoter, thanks to its natural ability to relax both mind and body. As mentioned before, DDH-B can boost GABA activity which also leads to better sleep. In fact, according to some studies, it will increase the time you spend in REM sleep and also reduce the time it takes you to fall asleep.

Supports brain health

DHH-B has the antioxidative ability and ability to activate GAMA receptors. Both of these properties are essential to your brain health. Antioxidative properties of the product will prevent your brain cells from damaging.

Fights Stress and Anxiety

DHH-B boosts GABA, a neurotransmitter that exerts a calming effect. Increased GABA activity quiets excitatory neurons in the brain, helps reduce anxiety, and promotes sleep. Dihydrohonokiol-B also reduces adrenaline, a hormone strongly associated with stress, and research indicates it may suppress unhealthful levels of cortisol, another significant stress-related hormone.


As we said above , DHH-B naturally extracted from magnolia tree bark, so it is safe when we take it as a nutrition supplement. But an exact dosage depends on person’s age, health, use purpose, materials content and other conditions, please consult your physician about the proper use

Some of the found side effects include headache and dizziness. If you are pregnant or breastfeeding, consider consulting with your healthcare provider before using DHH-B or any other Magnolia based supplements.

You should also avoid combining DDH-B with alcohol, as it can cause sleepiness and affect your motor skills. This is typical when consuming larger doses of the supplement.